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Cosmelan works by inhibiting the enzyme tyrosinase responsible for production of melanin in the skin through corrective and preventative action.

Corrective action – This corrective process reduces the amount of melanin synthesis, stimulates cell renewal and intensively combats the accumulation of melanin in the superficial skin layer to fade away existing unwanted pigmentation, resulting in a brighter and more even skin tone.

Preventative action – By inhibiting tyrosinase activation and reducing the function of tyrosinase, the melanin is prevented from reaching the skin surface, decreasing the formation of new unwanted pigmentation.

Dermamelan works similarly to Cosmelan but with a stronger corrective and regulating action as it contains higher amounts of the active ingredients found in Cosmelan, therefore, it is reserved for more severe pigmentation issues such as dermal melasma and severe acne scars.